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Dissolution

What is Dissolution?

Dissolution examines the release of an active pharmaceutical ingredient (API) from its formulation under controlled conditions. Thereby, dissolution contributes significantly to the performance evaluation of drug products in the regulated context of pharmacopoeias. Dissolution testing determines the release rate of one or multiple APIs from the respective dosage forms. The dissolution test is therefore an essential part of the quality control of different formulations, e.g. dosage forms with immediate, prolonged, or delayed release of the APIs. 

We offer:   

  • Dissolution of different dosage forms, e.g. tablets, capsules or granules. 
  • Dissolution with USP apparatus 1+2 (Basket + Paddle). Other methods on request (e.g. Paddle over Disk, Intrinsic Dissolution, Rotating Cylinders). 
  • Dissolution & Analytics: Quantification via various analytical methods of your choice (e.g. HPLC, UV, GC). 

 

Transparent Pricing

Rely on our transparent pricing with all-in-one prices and no hidden costs. 

 

Quality assurance and regulatory compliance 

With our specialized support, ensure the quality of your products and their regulatory compliance (EP & USP). Optimize your quality control processes through flexible combination options with our large analytical portfolio and benefit from our GMP-certified experience. Gain insights into the release of APIs and optimize your formulations.  

 

Flexible availability and 1:1 consulting 

Benefit from our flexible availability and personal 1:1 support, that our long-term customers confide in. Take advantage of our laboratory network with a variety of existing complex chromatographic methods – oftentimes without additional HPLC method development 

 

Specialized support and innovative solutions

Profit from the specialized support in our dedicated dissolution lab with direct contact to our lab manager Dr. Larissa Casper. We enjoy working with you on complex requirements and matrices – challenge us! Our lab additionally offers the possibility to work under yellow light, so that we can offer to optimally process light- and UV-sensitive substances. 

 

Experience and confidence

Our customers trust our valuable experience as drug product experts (DPE). You can rely on our many years of experience and the confidence of our loyal customers in pharma industry, who consult us as their reliable partner since many years. 

Our DPE-team: Your address for comprehensive drug product analyses 

Our specialized DPE-team and Currenta Analytics offer you a wide range of services to ensure the quality and safety of your drug product:

USP apparatus 1 with basket for dissolution testing
  • Dissolution testing 
  • Breaking strength 
  • Friability testing 
  • Disintegration analysis 
  • Content & bulk Uniformity 
  • Assay and related impurities 
  • Removable content 

 

 

How can we help you?

 

Precise analytical results and customized solutions 

Obtain precise results through the flexibility of coupling dissolution with other analytical methods. We tackle every challenge with you, e.g. dissolution with complex media through precise manual sampling. We implement your projects on tight schedules, and you benefit from customized solutions that precisely meet your analytical needs. Due to our timely data delivery, you can integrate the outsourced processes seamlessly into your project. 

 

Do you have any questions or need any other support?
Get in touch with us today!

Your contact for dissolution and the other services for your drug products, Dr. Casper, is ready to support you with her expertise. Whether it is for your specific inquiries or general information – we are here for you! 

Contact

Dr. Larissa Casper
Dr. Larissa Casper

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